Category: Clinical Trials

How an ‘Impossible’ Idea Led to a Pancreatic Cancer Breakthrough

The New York Times – Business:
The new strategy also holds promise for lung and colon tumors. Here’s how scientists discovered it.
American Factories Lag in Adopting A.I. This Drugmaker Is an Exception.

The New York Times – Business:
A Bristol Myers Squibb plant that makes cancer drugs was the only manufacturer in the U.S. recognized for innovation by the World Economic Forum this year.
F.D.A. Grants Early Access to Promising Drug for Pancreatic Cancer

The New York Times – Business:
Patients with one of the deadliest cancers have been pleading for an unapproved treatment that may prolong their lives.
New Gene Therapy Enables Children With a Rare Form of Deafness to Hear

The New York Times – Business:
The treatment, the first of its kind, was approved by the Food and Drug Administration on Thursday. “Our baby was born deaf, and now he can hear,” said one parent.
Two Drugs Stir Hope for Treatment of Deadly Pancreatic Cancer

The New York Times – Business:
In separate small clinical trials, two treatments showed promise that they could help patients with one of the most dire diagnoses in oncology.
A Cancer Detection Test Fails in Major Study

The New York Times – Business:
A closely watched clinical trial in Britain that screened blood for early detection of cancer did not show a reduction in later stages of the disease.
U.S. Health Officials Defend Rejection of Moderna’s Flu Vaccine

The New York Times – Business:
The F.D.A.’s refusal to examine the company’s mRNA shot drew widespread criticism from doctors and was divisive within the agency.
New Eli Lilly Drug Retatrutide Brought Major Weight Loss in Trial

The maker of Zepbound reported results from a study of retatrutide, which targets three hormones in the body and led to much more weight loss than any approved drug.
Ozempic Drug Fails to Quell Alzheimer’s in Novo Nordisk Trials

The studies were a significant setback for the optimistic view that semaglutide and other GLP-1 drugs could help prevent a number of brain diseases.
Study Finds Evidence That Text-Based Therapy Eases Depression

A large-scale randomized trial of texting therapy concluded that its outcomes were as good as video sessions in treating depression.
F.D.A. Moves to Speed Approvals for Cheaper Copycat Drugs

The agency announced moves to cut regulatory obstacles for the makers of biosimilar drugs, which are akin to generics and may help lower drug costs.
How Private Equity Oversees the Ethics of Drug Research

Many drug trials are vetted by companies with ties to the drugmakers, raising concerns about conflicts of interest and patient safety.